Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
Anichkov D.A., Shostak N.A., Zhuravleva A.D.
Therapy Department named after Nesterov, Russian State Medical University, Moscow. Gynecology department, Hospital N1 named after Pirogov, Moscow.
A role of menopause as a cardiovascular risk factor is reviewed. Menopause influence on the cardiovascular system may be mediated by body fat re-allocation, metabolic, hemodynamic and pro-inflammatory changes. Besides, estrogen deprivation has a direct effect on the arterial wall. Lifestyle modification, lipid-lowering and antihypertensive treatment should be considered for cardiovascular risk reduction in postmenopausal women.
Key words: Menopause, cardiovascular risk factors, lifestyle modification, pharmacological treatment.
Rational Pharmacother. Cardiol. 2005;1:37-42