Plasmapheresis in hypertriglyceridemia-related pancreatitis: a case report
Andrea Tampieri, Patrizia Cenni, Claudia Morselli, Tiziano Lenzi
Hypertriglyceridemia (HTG) is the third most common cause of acute pancreatitis (AP), accounting for up to 7% of cases. The clinical manifestations are similar to those of AP from other causes, but it may be difficult to recognize because of confounding laboratory investigations induced by HTG, such as a falsely normal serum amylase. Prompt recognition is important to provide adequate treatment. The maintenance of blood triglyceride (TG) levels below 500 mg/dl has been shown to accelerate the clinical improvement in patients with hypertriglyceridemic pancreatitis (HTGP). In many cases series apheresis was effective in reducing HTG and an early initiation is likely to be beneficial in order to prevent recurrence of AP and the development of necrotizing pancreatitis. Definitive guidelines for the treatment of HTGP and randomized trials that compare the effectiveness of apheresis with the medical therapy alone are still lacking.
Emergency Care Journal [eISSN 2282-2054] is the official journal of the Academy of Emergency Medicine and Care and it is published online by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.