International Journal of General Medicine
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Community-acquired pneumonia due to Legionella pneumophila, the utility of PCR, and a review of the antibiotics used
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Authors: Paul Zarogoulidis, Ioanna Alexandropoulou, Gioulia Romanidou, et al
Published Date January 2011 Volume 2011:4 Pages 15 - 19 Paul Zarogoulidis1,2, Ioanna Alexandropoulou1,2, Gioulia Romanidou3, Theocharis G Konstasntinidis1,2, Eirini Terzi3, S Saridou1, Athanasios Stefanis1, Kostas Zarogoulidis1,2, TC Constantinidis1,2
1Regional Laboratory of Public Health, East Macedonia-Thrace, Komotini, Greece; 2Laboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, Komotini, Greece; 3Department of Internal Medicine, General Municipal Hospital (“Sismanoglio” of Komotini), Komotini, Greece
Introduction: There are at least 40 types of Legionella bacteria, half of which are capable of producing disease in humans. The Legionella pneumophila bacterium, the root cause of Legionnaires’ disease, causes 90% of legionellosis cases.
Case presentation: We describe the case of a 60-year-old woman with a history of diabetes mellitus and arterial hypertension who was admitted to our hospital with fever and symptoms of respiratory infection, diarrhea, and acute renal failure. We used real-time polymerase chain reaction (PCR) to detect L. pneumophila DNA in peripheral blood and serum samples and urine antigen from a patient with pneumonia. Legionella DNA was detected in all two sample species when first collected.
Conclusion: Since Legionella is a cause of 2% to 15% of all community-acquired pneumonias that require hospitalization, legionellosis should be taken into account in an atypical pulmonary infection and not be forgotten. Moreover, real-time PCR should be considered a useful diagnostic method.
Keywords: Legionnaires’ disease, Lionella pneumophila
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