1-[(Cyclopropylmethoxy)methyl]-5-ethyl-6-(4-methylbenzyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Acta Crystallographica Section E

Structure Reports Online

Volume 68, Part 2 (February 2012)

organic compounds

xu5423 scheme

Acta Cryst. (2012). E68, o348 [ doi:10.1107/S1600536811055681 ]

1-[(Cyclopropylmethoxy)methyl]-5-ethyl-6-(4-methylbenzyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

N. R. El-Brollosy, A. A. El-Emam, O. A. Al-Deeb and S. W. Ng

Abstract: The pyrimidine ring in the title compound, C₁₉H₂₄N₂O₃, is nearly planar (r.m.s. deviation = 0.008 Å); the C atom at the 5-position deviates by 0.054 (3) Å from the mean plane and the C atom at the 6-position by 0.006 (3) Å in the opposite direction. The benzene ring is approximately perpendicular to the pyrimidine ring [dihedral angle = 83.90 (10)°]. The amino group is hydrogen-bond donor to the exocyclic O atom at the 2-position of an adjacent molecule, the hydrogen bond generating an inversion dimer. The cyclopropyl ring is disordered over two sets of sites with the major component having 71.5 (4)% occupancy.