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Infectious Diseases in Obstetrics and Gynecology
Volume 7 (1999), Issue 6, Pages 287-292
http://dx.doi.org/10.1155/S1064744999000538
Pattern of Parvovirus B19 Infection During Different Trimesters of Pregnancy in Kuwait
1Department of Obstetrics and Gynaecology, Faculty of Medicine, Kuwait University, P.O. Box 24923,Safat, 13110, Kuwait
2Department of Microbiology, , Kuwait University, Kuwait
Received 18 May 1999; Accepted 22 September 1999
Copyright © 1999 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objective: Aims of this study were to determine the IgG and IgM seropositivity to parvovirus B19 during the three trimesters of pregnancy.
Methods: Initially, a total of 1,047 pregnant women were included in a prospective study. Blood samples were obtained from 343, 406 and 298 cases in the first, second and third trimesters, respectively. To study the incidence of seroconversion, a second sample of blood was obtained 2–4 weeks later from the first 100 cases, who were IgG and IgM negative in the first trimester.
Results: The seroprevalence of parvovirus B19 IgG and IgM was 53.3% and 2.2%, respectively. The incidence of seroconversion was 16.5%. The rate of fetal loss was 15.4% in patients with acute infection, all of which occurred in the first two trimesters.
Conclusions: The percentage of IgG positive cases is significantly higher in first and second trimesters compared to the third trimester. The seroconversion rate was 16.5%. Infect. Dis. Obstet. Gynecol. 7:287–292, 1999.