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Convenient synthesis of some new pyrazolo[5,1-c]triazines, isoxazolo[3,4-d] pyrimidine and pyridine derivatives containing benzofuran moiety | Abdelhamid | European Journal of Chemistry

Convenient synthesis of some new pyrazolo[5,1-c]triazines, isoxazolo[3,4-d] pyrimidine and pyridine derivatives containing benzofuran moiety

Abdou Osman Abdelhamid, Abdelgawad Ali Fahmi, Amna Ali Mohamed Alsheflo


Pyrazolo[5,1-c][1,2,4]triazine, [1,2,4]triazolo[3,4-c][1,2,4]triazine, benzo[4,5]-imidazo[2,1-c][1,2,4]triazine, isoxazole, isoxazolo[3,4-d]pyridazine, pyrazole, pyridine, substituted urea and phenyl carbamate derivatives containing benzofuran moiety were synthesized via reaction of sodium salt of 5-hydroxy-l-benzofuran-2-ylpropenone or 1-(benzofuran-2-yl)-3-(dimethylamino)prop-2-en-1-one with diazotized heterocyclic amines, hydroximoyl chlorides and active methylene compounds. The structures of all the newly synthesized compounds were confirmed by elemental analyses, spectral data, and alternative synthetic routes, whenever possible.



Triazines; Pyridines; Pyrazoles; Isoxazoles; Hydrazones; Benzoimidazo[2,1-c][1,2,4]triazine

European Journal of Chemistry, 3 (2), (2012), 129-137

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[1]. Synthesis, characterization and antimicrobial evaluation of 1-((5,3-diaryl)-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one
Assia Sid, Nouara Ziani, Ouafa Demmen-Debbih, Mahieddine Mokhtari, Kaddour Lamara
European Journal of Chemistry  Volume: 4  Issue: 3  First page: 268  Year: 2013  

[2]. Synthesis and antimicrobial activities of pyrido[2,3-d]pyrimidine, pyridotriazolopyrimidine, triazolopyrimidine, and pyrido[2,3-d:6,5d']dipyrimidine derivatives
Anhar Abdel-Aziem, Marwa Sayed El-Gendy, Abdou Osman Abdelhamid
European Journal of Chemistry  Volume: 3  Issue: 4  First page: 455  Year: 2012  



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