Convenient synthesis of some new pyrazolo[5,1-c]triazines, isoxazolo[3,4-d] pyrimidine and pyridine derivatives containing benzofuran moiety
Abstract
Pyrazolo[5,1-c][1,2,4]triazine, [1,2,4]triazolo[3,4-c][1,2,4]triazine, benzo[4,5]-imidazo[2,1-c][1,2,4]triazine, isoxazole, isoxazolo[3,4-d]pyridazine, pyrazole, pyridine, substituted urea and phenyl carbamate derivatives containing benzofuran moiety were synthesized via reaction of sodium salt of 5-hydroxy-l-benzofuran-2-ylpropenone or 1-(benzofuran-2-yl)-3-(dimethylamino)prop-2-en-1-one with diazotized heterocyclic amines, hydroximoyl chlorides and active methylene compounds. The structures of all the newly synthesized compounds were confirmed by elemental analyses, spectral data, and alternative synthetic routes, whenever possible.
Keyword(s)
European Journal of Chemistry, 3 (2), (2012), 129-137
DOI: http://dx.doi.org/10.5155/eurjchem.3.2.129-137.579
Cited-By
[1]. Synthesis, characterization and antimicrobial evaluation of 1-((5,3-diaryl)-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one
Assia Sid, Nouara Ziani, Ouafa Demmen-Debbih, Mahieddine Mokhtari, Kaddour Lamara
European Journal of Chemistry Volume: 4 Issue: 3 First page: 268 Year: 2013
[2]. Synthesis and antimicrobial activities of pyrido[2,3-d]pyrimidine, pyridotriazolopyrimidine, triazolopyrimidine, and pyrido[2,3-d:6,5d']dipyrimidine derivatives
Anhar Abdel-Aziem, Marwa Sayed El-Gendy, Abdou Osman Abdelhamid
European Journal of Chemistry Volume: 3 Issue: 4 First page: 455 Year: 2012
References
[1]. Rao, D. R.; Raychaudhuri, S. P.; Verma, V. S. Int. J. Tropical Plant Dis. 1994, 12, 177-185.
[2]. Hinshaw, B. C; Lconoudakis, O.; Townsend, L. B. Abstracts 112d National Meeting of the American Chemical Society, D. C. Washington. Sept. No MEDI-15, 1971.
[3]. Ito, I. Japanese Patent 70301011971; Chem. Abstr. 1974, 22827, 1971.
[4]. Tseng, C. P. U. S. Pat. 1989, 4838925; Chem. Abstr. 1990, 112, 7508.
[5]. Sakane, K.; Kawabata, K.; Inamoto, Y. Eur. Pat. 1989, 332156; Chem. Abstr. 1990, 112, 216538.
[6]. Fujikawa, Y.; Suzuki, M.; Sakashita, M.; Tanaka, S.; Wakamatsu, M.; Miyasaka, S. Jpn. Kokai Tokkyo Koho JP 01, 221, 381 [89, 221, 381] (CI. C07D487/04) 1989; Chem. Abstr. 1990, 112, 158268j.
[7]. Tseng, S. S.; Brabander, J. H.; Epstein, W. J. U. S. Pat. 1990, 4963553; Chem. Abstr. 1991, 114, 228937.
[8]. Taylor, R. C.; Stauffer, F. H.; Tomezuk, B. E. U. S. Pat. 1992, 5114944; Chem. Abstr. 1992, 117, 90318.
[9]. Hibino, H.; Myamoto, Y.; Myajima, M.; Maeda, H. Jpn. Kokai Tokkyo Koho Jp 05, 213, 756 [93, 213, 756] (CI. A61K31/505); Chem. Abstr. 1993, 119, 256547p.
[10]. Allen, E. E.; Maccoss, M.; Chakravarty, P. K.; Patchett, A. A.; Greenlee, W. J.; Walsh, T. F. Eur. Pat. 1992, 490587; Chem. Abstr. 1992, 117, 151008.
[11]. Gatta, F.; Perotti, F.; Gradoni, L.; Gramiccia, M.; Orsini, S.; Palazzo, G.; Rossi, V. Eur. J. Med. Chem. 1990, 25, 419-424.
http://dx.doi.org/10.1016/0223-5234(90)90005-N
[12]. Ahmed, A. H.; Hozayen, W. H.; El-Gandour, A. H. H; Abdelhamid, A. O. J. Heterocycl. Chem. 2007, 44, 803-810.
http://dx.doi.org/10.1002/jhet.5570440408
[13]. Abdelhamid, A. O.; Sayed, A. R.; Zaki, Y. H. Phosphorus Sulfur Silicon Relat. Elem. 2007, 182, 1447-1457.
http://dx.doi.org/10.1080/10426500701242145
[14]. Abdelhamid, A. O.; Abdelaziz, H. M. Phosphorus Sulfur Silicon Relat. Elem. 2007, 182, 2791-2800.
http://dx.doi.org/10.1080/10426500701521548
[15]. Abdelhamid, A. O.; El-Ghandour, A. H.; El-Reedy, A. A. M. J. Chin. Chem. Soc. 2008, 55, 406-413.
[16]. Abdelhamid, A. O.; Fahmi, A. A.; Halim, K. N. M. Eur. J. Chem. 2011, 2(3), 317-323.
http://dx.doi.org/10.5155/eurjchem.2.3.317-323.420
[17]. Keshk, E. M. Heteroatom Chem. 2004, 15, 85-91.
http://dx.doi.org/10.1002/hc.10219
Refbacks
- There are currently no refbacks.