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Rational Pharmacotherapy in CardiologyInfluence of antihypertensive drugs on arterial stiffness in patients with arterial hypertension

Influence of antihypertensive drugs on arterial stiffness in patients with arterial hypertension

N.V. Egorkina, V.M. Gorbunov*, E.S. Abirova

State Research Center for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990 Russia

Results of studies devoted to effects of various antihypertensive drugs on arterial stiffness in patients with arterial hypertension are presented. Advantages of angiotensin converting enzyme inhibitors and angiotensin receptor blockers are shown. Results of comparative studies on influence of combined therapy and monotherapy on arterial stiffness in hypertensive patients are also reviewed. Standard methods of arterial stiffness evaluation are estimated as mostly appropriate ones.

Key words: arterial hypertension, arterial stiffness, antihypertensive therapy, pulse wave velocity, augmentation index.

Rational Pharmacother. Card. 2009;5:67-72

*Corresponding author: vgorbunov(a)gnicpm.ru


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«Stolichnaya Izdatelskaya Kompaniya»

ISSN 1819-6446(Print) ISSN 2225-3653 (Online)