Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
Statins and myopathy: molecular mechanisms
O.M. Drapkina*, E.M. Chernova, O.N. Korneeva
I.M. Setchenov First Moscow State Medical University. Trubetskaya ul 8-2, Moscow, 119991, Russia.
The safety of statin therapy is considered. In particular the reasons of a complication such as myopathy are discussed in detail. The molecular mechanisms of statin myopathy, as well as its risk factors are presented. The role of coenzyme Q10 in the myopathy development and coenzyme Q10 application for the prevention of this complication are considered.
Key words: statins, myopathy, coenzyme Q10, rosuvastatin.
Rational Pharmacother. Card. 2012;8(3):
* Corresponding author: drapkina@bk.ru
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«Stolichnaya Izdatelskaya Kompaniya»
ISSN 1819-6446(Print) ISSN 2225-3653 (Online)
«Stolichnaya Izdatelskaya Kompaniya»
ISSN 1819-6446(Print) ISSN 2225-3653 (Online)