Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
Dihydropyridine calcium antagonists: the role in current therapy of cardio-vascular diseases
E.V. Shilova, S.Y. Martsevich
State Research center of preventive medicine of Rosmedtechnology, Moscow
Classification of calcium antagonists (CA) is presented. Results of the large clinical trials (STONE, STOP-Hypertension-2, ALLHAT, ASCOT-BPLA etc.) devoted to estimation of CA effects on the risk of cardiovascular complications are analyzed. The significant place of dihydropyridine CA in current guidelines on arterial hypertension and ischemic heart disease therapy is underlined. Results of a pilot study on comparison of two amlodipines (original Norvasc and generic Stamlo M) are discussed.
Key words: calcium antagonists, dihydropiridines, arterial hypertension, ischemic heart disease, cardiovascular risk, amlodipine.
Rational Pharmacother. Card. 2008;2:53-57
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«Stolichnaya Izdatelskaya Kompaniya»
ISSN 1819-6446(Print) ISSN 2225-3653 (Online)
«Stolichnaya Izdatelskaya Kompaniya»
ISSN 1819-6446(Print) ISSN 2225-3653 (Online)