Title |
| The role of the microenvironment in tumor immune surveillance |
Authors | Oluwadayo Oluwadara1, Luca Giacomelli2, Xenia Brant1, 3, Russell Christensen4, Raisa Avezova1, George Kossan1, Francesco Chiappelli1* | |
Affiliation | 1School of Dentistry, Division of Oral Biology and Medicine; 2Tirrenian Stomatologic Institute, Lido di Camaiore (Lucca), Italy; 3CEO IPSEMG Belo Horizonte, Brazil; 4UCLA School of Dentistry, Division of Oral and Maxillofacial Pathology | |
| ||
Article Type | Hypothesis
| |
Date | Received July 25, 2010; Accepted August 03, 2010; Published January 06, 2011 | |
Abstract | The evidence appears compelling that the microenvironment, and associated biological cellular and molecular factors, may contribute to the progression of a variety of tumors. The effects of the microenvironment may directly influence the plasticity of T cell lineages, which was recently discussed (O�Shea & Paul, 2010 ). To review the putative role of the microenvironment in modulating the commitment of tumor immune surveillance, we use the model of oral premalignant lesions. | |
Keywords | Oral lichen planus, oral squamous cell carcinoma, proteomic voting, tumor microenvironment, T cell lineages, tumor immune surveillance | |
Citation | Oluwadara et al. Bioinformation 5(7): 285-290 (2011) | |
Edited by | Francesco chiappelli
| |
ISSN | 0973-2063
| |
Publisher |
| |
Copyright | Publisher
| |
Copyright Transfer Agreement | The authors of published articles in Bioinformation automatically transfer the copyright to the publisher upon formal acceptance. However, the authors reserve right to use the information contained in the article for non commercial purposes.
| |
License | This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
|