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Clinical Ophthalmology
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Upper eyelid retraction disclosed after edrophonium chloride administration in a patient with Graves' orbitopathy and myasthenia gravis
Case report
(2884) Total Article Views
Authors: Kang H, Takahashi Y, Iwaki M, Asamura S, Kakizaki H
Published Date May 2012 Volume 2012:6 Pages 807 - 810
DOI: http://dx.doi.org/10.2147/OPTH.S29408
| Received: | 23 December 2011  |
|---|---|
| Accepted: | 14 January 2012 |
| Published: | 28 May 2012 |
1Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan; 2Department of Ophthalmology, Presbyterian Medical Center, Jeonju, Korea; 3Department of Plastic and Reconstructive Surgery, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan
Abstract: Patients with Graves' orbitopathy have a higher probability of myasthenia gravis than does the normal population. Overlapping clinical features cause diagnostic confusion in such a situation. We herein report a patient with Graves' orbitopathy and myasthenia gravis (GO-MG) with normal left eyelid height, but in whom upper eyelid retraction was shown after edrophonium chloride administration. Upper eyelid retraction in GO-MG is occasionally masked by a myasthenia effect. The upper eyelid height must be carefully monitored in patients with Graves' orbitopathy to detect the presence of concomitant myasthenia gravis.
Keywords: Graves' orbitopathy, myasthenia gravis, eyelid retraction, edrophonium chloride
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