Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
Application of calcium antagonists in prevention of cardiovascular complications during cardiac surgery
S.V. Nedogoda
Volgograd Medical State University
Results of randomized clinical trials on the usage of calcium antagonists (CA) in order to prevent perioperative complications during aortocoronary bypass procedure and operations on heart valves are analyzed. CA reduced the risk of perioperative myocardial infarctions and episodes of reversible myocardial ischemia. After angioplasty of coronary arteries CA (particularly amlodipine) show positive effects on restenosis incidence and reduce about 3 times a number of repeated angioplasty and aortocoronary bypass operations. The use of CA was accompanied by more often need in heart electro stimulation without any subclass differences. It is also registered that nimodipine can strengthen intraoperative blood loss.
It is concluded, that CA have significant evident base that allows recommending them to patients undertaken by cardiological surgery.
Key words: calcium antagonists, intraoperative complications, aortocoronary bypass, angioplasty.
Rational Pharmacother. Card. 2006; 3: 56-64Download free full text (PDF)
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«Stolichnaya Izdatelskaya Kompaniya»
ISSN 1819-6446(Print) ISSN 2225-3653 (Online)
«Stolichnaya Izdatelskaya Kompaniya»
ISSN 1819-6446(Print) ISSN 2225-3653 (Online)