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Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives | El-Shaaer | European Journal of Chemistry

Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives

Hafez Mohamed El-Shaaer, Salah Abdel-Ghaffar Abdel-Aziz, Faten Ismail Hanafy, Tarik El-Sayed Ali, Ali Zaky El-Fauomy

Abstract


Some new antifungal agents have been prepared through reaction of 4-oxo-4 H-chromene-3-carbaldehydes ( 1a, b) with some active primary amines ( 2a- e) and amides/thioamides ( 6a- d) in different conditions. Structures of the products were established on the basis of elemental analysis, IR, 1H NMR, mass spectra and semi-empirical AM1-MO calculations. 2_2_158_162_800

Keyword(s)


Synthesis; Chromone; Chromone Derivatives; 3-Formylchromones; Antifungal activity; AM1-MO Calculation

European Journal of Chemistry, 2 (2), (2011), 158-162

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DOI: http://dx.doi.org/10.5155/eurjchem.2.2.158-162.381

 

Cited-By

[1]. An efficient synthesis of some new isolated and fused 2-oxo-2H-chromene derivatives as antimicrobial and antitumor agents
Hafez Mohamed El-Shaaer
European Journal of Chemistry  Volume: 4  Issue: 2  First page: 138  Year: 2013  
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[2]. An efficient cyclocondensation reactions, antimicrobial activity and molecular orbital calculations of α-benzopyrone derivatives
Hafez Mohamed El-Shaaer, Salah Sayed Ibrahim, Wafaa Ramzy Abd-Elmonem, Christine Gamal Ibrahim
European Journal of Chemistry  Volume: 3  Issue: 2  First page: 172  Year: 2012  
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