Scientific and practical peer-reviewed journal for cardiologists and general practice physicians. Issued since 2005
ISSN 1819-6446 (Print) ISSN 2225-3653 (Online)
S.J. Martsevich*
State Research Center for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990 Russia
Chair of Evidence Based Medicine, I.M. Setchenov First Moscow State Medical University. Petroverigsky per. 10, Moscow, 101990 Russia
The ACC/AHA clopidogrel clinical alert about the possibility of ineffective treatment with clopidogrel is discussed. The reason of this resistance to clopidogrel therapy and possible ways to overcome it is considered.
Key words: clopidogrel, genetic CYP2C19 polymorphism, antiplatelet therapy.
Rational Pharmacother. Card. 2010;6(4):607-609
*Corresponding author: smartsevich@gnicpm.ru