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BIOTECHNOLOGY : AN OVERVIEW | Bruce | Buletin Penelitian Kesehatan

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  • BIOTECHNOLOGY : AN OVERVIEW

    John I. Bruce

    Abstract


    Biotechnology as a science includes various aspects of the management and manipulation of biological systems. Recent advances in immunology, molecular biology, cell culture and other associated areas provide an opportunity for scientists to move biology out of the laboratory and into the realms of society. This has many implications which mankind on a whole may not be prepared to cope with at this time. This new capability has been referred to as "Biotechnology". Biotechnology has also been defined as "the integrated use of biochemistry, microbiology, and chemical engineering in order to achieve the capacities of microbes and culture cells". Genetic engineering which includes gene splicing and recombinant DNA-cloning is an example of a recent offshoot of biotechnology.

    Because of the advent of biotechnology, one can now think of the prospect of engineering tomorrows vaccines. In the past, vaccine development has been laborious and in many instances an unrewarding task. After years of effort only a handful of safe, effective vaccines have emerged. In the biotechnology arena, new methodologies and strategies for immunizing humans and domestic animals against infectious diseases are providing new hope for discovering successful vaccines. While most of the effort in the past has focused on viral vaccine development, attention is now being directed towards vaccines for protection against parasitic diseases.

    Currently, considerable effort is being made to develop vaccines for malaria, coccidiosis (in fowl), cholera, malaria, schistosomiasis and trypanosomiasis among others.

    Keywords


    Biotechnology; DNA-cloning; Genetic engineering

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    Buletin Penelitian Kesehatan (Bulletin of Health Research, ISSN: 0125-9695. EISSN: 2338-3453) diterbitkan oleh National Institute of Health Research and Development, Ministry of Health of Republic of Indonesia
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